Description
Product Overview Vasoactive Intestinal Peptide (VIP) is a foundational neuropeptide belonging to the glucagon/secretin superfamily. By targeting the G-protein-coupled VPAC receptors, it acts as a critical neuroendocrine mediator, making it an essential compound for researchers investigating autonomic nervous system and immune system cross-talk.
Mechanism of Action
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Smooth Muscle Assays: Research demonstrates VIP’s profound ability to induce relaxation in isolated gastrointestinal, respiratory, and vascular smooth muscle tissues.
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Macrophage Polarization: It is heavily studied for its dose-dependent ability to shift macrophages from a pro-inflammatory (M1) to an anti-inflammatory (M2) phenotype.
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Cytokine Regulation: Studies show it downregulates the production of inflammatory mediators like TNF-alpha and IL-6 while upregulating protective factors in environmentally stressed cellular models.
Quality Assurance
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Sequence: His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2
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Yield: 10mg per vial
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Purity: >99% Verified by HPLC
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Form: Sterile White Lyophilized Powder
