Description
Product Overview In the study of dermatological cellular defense, isolating specific melanocortin pathways is critical. Melanotan 1 (MT-1) features strategic amino acid substitutions that grant it a significantly longer half-life and greater receptor affinity than endogenous α-MSH, making it an ideal compound for extended in-vitro cellular assays.
Mechanism of Action
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MC1R Agonism: Research indicates MT-1 binds preferentially to the MC1 receptor located on the surface of melanocytes.
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Melanogenesis Assays: Upon binding, it triggers a cAMP-dependent signaling cascade, leading to the synthesis and cellular distribution of eumelanin (the photoprotective pigment) in laboratory tissue models.
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Targeted Activity: Unlike cyclic analogs (such as MT-2), the linear structure of MT-1 restricts its ability to cross the blood-brain barrier, limiting its affinity for central nervous system receptors (MC3R/MC4R).
Quality Assurance
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Sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
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Purity: >99% Verified by HPLC
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Form: Sterile White Lyophilized Powder
Disclaimer:
WARNING – FOR RESEARCH USE ONLY: This product is sold exclusively as an analytical reference standard and research chemical. It is NOT an FDA-approved drug, cosmetic, or medical device. Not for human consumption, therapeutic use, or veterinary application. Any reference to physiological effects is strictly for educational context.
