CJC-1295 No DAC (Mod GRF 1-29) – Lyophilized Peptide

Price range: $40.00 through $70.00

CJC-1295 (No DAC), also known as Modified GRF 1-29, is a synthetic, tetrasubstituted analog of Growth Hormone-Releasing Hormone (GHRH). It is engineered with four amino acid substitutions to prevent rapid degradation by DPP-IV enzymes while maintaining a short half-life. This makes it the premier peptide for researching natural, pulsatile growth hormone secretion in in-vitro pituitary models. Our lyophilized preparation is HPLC-verified for >99% purity. Strictly for laboratory research use only; not for human consumption.

Description

Product Overview In endocrine research, controlling the duration of receptor activation is critical. CJC-1295 (No DAC) represents a highly refined version of the shortest fully functional GHRH fragment (amino acids 1-29). By omitting the Drug Affinity Complex (DAC), this peptide avoids continuous receptor activation, preventing pituitary receptor downregulation.

Mechanism of Action

  • Pituitary Stimulation: It acts directly on the anterior pituitary gland to stimulate the secretion of endogenous growth hormone.

  • Pulsatile Kinetics: With a physiological half-life of approximately 30 minutes, it is ideal for studies requiring a simulated “pulse” rather than a sustained baseline elevation.

  • Synergistic Models: Often researched in conjunction with GHRPs (like Ipamorelin) to study the amplification of the hormonal pulse.

Quality Assurance

  • Identity: Modified GRF 1-29 (Tetrasubstituted)

  • Purity: >99% Verified by HPLC

  • Form: Sterile White Lyophilized Powder

Disclaimer:

WARNING – FOR RESEARCH USE ONLY: This product is sold exclusively as an analytical reference standard and research chemical. It is NOT an FDA-approved drug or medical device. Not for human consumption, therapeutic use, or veterinary application. Any reference to physiological effects is strictly for educational context.

Additional information

MG

5, 10